Articles Tagged With:
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IRB Pandemic Impact Report
In this question and answer special report, a dozen IRB administrators, directors, chairs, and other leaders from across the United States were asked about their facilities’ experiences during the COVID-19 pandemic’s early weeks.
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IRB Experts Offer Advice for Changing Research Landscape
It is clear that clinical trials now exist in a different world from what researchers, IRBs, and sponsors experienced in 2019. The key challenges are how to restart clinical trials, how to return to in-person visits, and how to manage the growing number of studies related to COVID-19.
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Intermittent Fasting: A Faster Way to a Longer Life?
Intermittent fasting, which once was strictly in the purview of religion and health fads, has undergone a rapid increase in scientific interest. Studies now demonstrate the positive impact that various methods of intermittent fasting can have on overall health.
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ACS Prepares Surgeons for Resuming Elective Procedures
The COVID-19 pandemic forced many facilities to press pause on regular operations. Now, some are ready to chart a course back toward some sense of normalcy.
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Infectious Disease Alert Updates
Complications of Typhoid Fever; Do I Smell a Rat? Or Is the Rat Smelling Me? Cloth Masks — Just for Looks?
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Lefamulin: Formulary Considerations
The Food and Drug Administration (FDA) recently approved lefamulin for the treatment of adults with community-acquired bacterial pneumonia (CABP).
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Antibiotic Therapy to Reduce the Incidence of Ventilator-Associated Pneumonia After Cardiac Arrest
In this prospective, randomized trial, intravenous amoxicillin-clavulanate (dosed three times daily and given for two days) administered to patients admitted with out-of-hospital cardiac arrest due to a shockable rhythm reduced the incidence of early ventilator-associated pneumonia.
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Carbapenem-Resistant Enterobacterales (CRE) in the USA — A Molecular and Clinical Analysis
Patient mortality rates were high among patients from whom carbapenem-resistant Enterobacterales (CRE) were cultured, regardless of whether the organism was causing infection or was a only a colonizer. In addition, mortality was similar regardless of whether a carbapenemase gene was present. Finally, not all “CRE” were truly CRE.
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Clostridioides difficile: Risk Factors for Disease
Approximately one-tenth of asymptomatic patients with Clostridioides difficile colonization went on to develop disease. A wide range of antibiotic exposures represent a significant risk.
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Inappropriately Broad Empiric Antibiotics Are Associated with Higher Mortality in Community-Onset Sepsis
A retrospective cohort study found that broad-spectrum antibiotics were unnecessarily prescribed to patients with community-onset sepsis and was associated with worse outcomes and higher mortality.